Twist and Shout by The Beatles

For one, you get to yell. And everybody knows the song and can sing along. When Twist and Shout was used in Ferris Bueller's Day Off in the 80's, it shot up the charts. This from a song released in the 60's. Everybody knows Twist and Shout!

Psycho Killer by Talking Heads

The ability to passionately deliver this Talking Heads classic, combined with the "funny" lyrics, make Psycho Killer one of my favorite songs to sing in my car at the top of my lungs.

House of the Rising Sun by The Animals

Another song most people know the lyrics to, Eric Burdon was one of the great 60's white soul singers. When played loudly the organ pierces your brain and my voice gets all raspy by the end of singing it!