We've all been there. You're at a house party, a bar or a club, and suddenly it hits you - you have to get out of there. Start the long walk home, grabbing some poutine on the way to soak up whatever you drank in the last half-hour, call a cab, whatever. It's time to call it quits.

Double Vision
Once you have to squint and close one eye to get a grip on the room, it's time to leave.

Your friends have mysteriously disappeared and you're left talking to that sketchy group of guys in the corner
Being the person who closes down the bar is admirable, but once your gang is gone, you might want to consider the reasons they left.

Spilling your beer
Seriously, once you've lost control of that libation cup, your choice is to either dowse yourself completely and declare yourself Poseidon, King of the Sea, or dab it off and call it quits.